The primary advantage of genetic profiling is that it makes tailored treatment possible, which is more accurate than conventional methods. Chemotherapy and other conventional breast cancer treatments target cells that divide quickly. Chemotherapy can harm healthy cells and cause side effects like fatigue, nausea, and hair loss, even though it is often effective. This is changed by genomic profiling, which assists doctors in concentrating on treatments that specifically target the genetic vulnerabilities of the cancer, resulting in a more effective course of treatment with fewer side effects.

For instance, doctors can provide individualized medicines like PARP inhibitors, which take advantage of the cancer cells’ incapacity to repair DNA, to patients with breast cancer who test positive for certain gene abnormalities (such as the BRCA1 or BRCA2 mutations). In these situations, a more focused and efficient strategy is taken because the treatment is especially designed to address the genetic weaknesses of the malignancy.

Genomic profiling helps physicians determine which malignancies are likely to respond to particular treatments in addition to finding particular alterations. For instance, certain breast tumors grow in response to progesterone or estrogen because they are hormone receptor-positive. Treatments that block these hormones, like aromatase inhibitors or tamoxifen, can be quite effective for certain tumors. Using genomic profiling, doctors can help improve survival rates and reduce the need for more aggressive treatments like chemotherapy.